One Piece is one of the most popular manga in the world. It tells about Luffy and his crews of pirate, who aspire to be the greatest pirates in the world.
One Piece has many aspects that make it interesting, but for me the most interesting part is the world concept. The world is in an era of marines and pirates. Among all ocean in the world, there is an area which by far are more dangerous than any other place in the world. The weather is unpredictable, the sea monsters are ferocious and normal compass does not work. Even just to enter will require the greatest seamen of the world.
This concept is interesting because that is pretty much how I see the world. Yes, of course we do not have sea monsters out there *perhaps*. But you see, pretty much in every field possible, there are always some people that do their things in an entirely different game from the common people. They are "the monster". Take football for example. In football, the "grand line" is World Cup, and athletes who play in World Cup play an entirely different level from the "tarkam" player. This situation is present in many other field. There are businessmen, scientisst, surgeons, who are monsters. And when you do "their game", you will feel a terrifying level of awesomeness. So, I can relate to the page when Luffy and the gangs enter the "New World" the second level of Grand Line. Deliciously awesome!